DUDE, you are a BOSS.  Bypass Single Root folder was exactly what was doing it.  The comixology themese says it's require but I'm not populating the publisher list so once I disabled it, it's all gravy.  How interesting, my F5 LB was not liking the redirect.

Thanks again dude!

Tom,

I viewed the webpage directly from the VM hosting the Ubooquity instance and it works.  What's interesting is that I do not have a proxy between them, but I do have a load balancer.  What could the load balancer be doing to disrupt the publisher/comic flow but allow the latest additions to work without issue?  How bizarre.

Andy

Dude, thank you so much, I was thinking no one would be commenting :(.  A blank page comes up with this in the middle:

This site can’t be reached

mycomics.mydomain.com refused to connect.

• Search Google for MyComicsServer

ERR_CONNECTION_REFUSED

Thoughts?